Before you decide which "charities" will receive your donations this year, have a look at this chart. (Click on the image to enlarge)
Charity is a big business in the US. While we do a lot of good with the money Americans give, there is a lot of personal profit being made at the same time. Be careful to whom you donate.
Note: I have not vetted this data. You should be responsible for researching whatever charity you give money to.